Tcherassi Hotel + Spa, Cartagena, Columbia. Each of the seven generous rooms in the 250-year- old colonial mansion is named after a luxe fabric; all have private balconies and rainshowers. The tri-level penthouse suite even has its own pool. The in-house Vera Italian restaurant features a vertical garden. Close to Plaza Fernandez de Madrid and the 17th-century San Felipe de Barajas castle. I'm feeling Romancing the Stone meets Kelly Wearstler.